About Enhancer
| Enhancer ID: | E_03835 |
| Species: | Homo sapiens |
| Position : | chr7:117075400-117076000   |
| Year: | 2015 |
| Title: | Oxidative stress regulates CFTR gene expression in human airway epithelial cells through a distal antioxidant response element. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 25259561 |
| Tissue: | bronchus |
| Tissue Ontology ID: | UBERON:0002185 |
| Cell Source: | 16HBE14o- |
| CVCL ID: | CVCL_0112 |
| Cell Type: | bronchial epithelial cell |
| Cell Ontology ID: | CL:0002328 |
| Experiment Type: | Enhancer activity assay; Endogenous enhancer perturbation |
| Low Throughput Method: | Luciferase Reporter Assay, RT-RT-qPCR; Site-directed/motif mutagenesis |
About Target Gene
| Target gene : | CFTR |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
9 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04477 | chr7:117074000-117077000 | nasal cavity epithelium | nasal epithelial cell | NA |
| E_00034 | chr7:117075400-117076000 | bronchus | bronchial epithelial cell | NA |
| E_00035 | chr7:117075400-117076000 | pleural effusion | epithelial cell | NA |
| E_00036 | chr7:117075400-117076000 | bronchus | bronchial epithelial cell | NA |
| E_00037 | chr7:117075400-117076000 | pleural effusion | epithelial cell | NA |
| E_00038 | chr7:117075400-117076000 | bronchus | bronchial epithelial cell | NA |
| E_00039 | chr7:117075400-117076000 | pleural effusion | epithelial cell | NA |
| E_03882 | chr7:117075514-117075933 | NA | NA | NA |
| E_03883 | chr7:117075514-117075933 | NA | NA | NA |
Expression of Target Genes for the Enhancer