About Enhancer
| Enhancer ID: | E_03838 |
| Species: | Mus musculus |
| Position : | chr11:6639091-6639657   |
| Year: | 2018 |
| Title: | Progressing super-enhancer landscape during mammary differentiation controls tissue-specific gene regulation. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 30285185 |
| Cell Source: | Mammary |
| Experiment Type: | TF-binding/chromatin assay; Endogenous enhancer perturbation |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP; RT-qPCR/qPCR |
About Target Gene
| Target gene : | Wap |
About TF
| TF name : | Nr3c1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Nr3c1 | AndrogenReceptor | netpath | 167 |
| Nr3c1 | AP-1 transcription factor network | pid | 71 |
| Nr3c1 | BMAL1:CLOCK,NPAS2 activates circadian gene expression | reactome | 42 |
| Nr3c1 | Cellular roles of Anthrax toxin | pid | 25 |
| Nr3c1 | FOXA2 and FOXA3 transcription factor networks | pid | 45 |
| Nr3c1 | Glucocorticoid receptor regulatory network | pid | 85 |
| Nr3c1 | IL2 | netpath | 81 |
| Nr3c1 | Nuclear Receptor transcription pathway | reactome | 51 |
| Nr3c1 | PTK6 Expression | reactome | 5 |
| Nr3c1 | Regulation of Androgen receptor activity | pid | 54 |
| Nr3c1 | Regulation of nuclear SMAD2/3 signaling | pid | 82 |
| Nr3c1 | Signaling events mediated by HDAC Class II | pid | 58 |
| Nr3c1 | Neuroactive ligand-receptor interaction | kegg | 272 |
| Nr3c1 | Hs_Endoderm_Differentiation_WP2853_88152 | wikipathways | 62 |
| Nr3c1 | Hs_Serotonin_Receptor_4-6-7_and_NR3C_Signaling_WP734_74438 | wikipathways | 15 |
| Nr3c1 | Hs_White_fat_cell_differentiation_WP3946_90940 | wikipathways | 30 |
| Nr3c1 | Hs_Transcription_factor_regulation_in_adipogenesis_WP3599_88581 | wikipathways | 9 |
| Nr3c1 | Hs_Sudden_Infant_Death_Syndrome_(SIDS)_Susceptibility_Pathways_WP706_86078 | wikipathways | 33 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer