About Enhancer
| Enhancer ID: | E_03876 |
| Species: | Homo sapiens |
| Position : | chr8:126650000-129950000   |
| Year: | 2023 |
| Title: | The Mediator complex regulates enhancer-promoter interactions. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 37430065 |
| Tissue: | colon |
| Tissue Ontology ID: | UBERON:0001155 |
| Cell Source: | Human colorectal carcinoma cell |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | Capture-C, Micro-Capture-C, Tiled-MCC, ChIP-seq, CUT&Tag, ATAC-seq, TT-seq |
| Low Throughput Method: | Western blot |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
80 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02302 | chr8:126800000-126900000 | kidney | malignant cell | rhabdoid tumor |
| E_04219 | chr8:127247950-127248600 | pancreas | pancreatic ductal cell | pancreatic ductal adenocarcinoma |
| E_04249 | chr8:127247950-127248600 | pancreas | pancreatic ductal cell | pancreatic ductal adenocarcinoma |
| E_03689 | chr8:127329840-127331840 | cerebrospinal fluid | medulloblastoma cell | group 3 medulloblastoma |
| E_03690 | chr8:127329927-127331927 | cerebrospinal fluid | medulloblastoma cell | group 3 medulloblastoma |
| E_03691 | chr8:127330655-127330840 | brain | medulloblastoma cell | Medulloblastoma |
| E_00840 | chr8:127668529-127669329 | breast | malignant breast epithelial cell | estrogen receptor-positive breast cancer |
| E_00843 | chr8:127668529-127669329 | breast | breast adenocarcinoma epithelial cell | Estrogen receptor-positive breast cancer |
| E_00883 | chr8:127668529-127669329 | breast | malignant cell | breast carcinoma |
| E_00760 | chr8:127898362-127899967 | blood | malignant cell | NA |
| E_00800 | chr8:127898362-127899967 | blood | malignant cell | NA |
| E_00761 | chr8:127960009-127960984 | blood | malignant cell | NA |
| E_00801 | chr8:127960009-127960984 | blood | malignant cell | NA |
| E_00903 | chr8:128018000-128023000 | prostate gland | malignant cell | prostate cancer |
| E_00904 | chr8:128018000-128023000 | prostate gland | malignant cell | prostate cancer |
| E_00905 | chr8:128018000-128023000 | prostate gland | malignant cell | prostate cancer |
| E_04611 | chr8:128041672-128043891 | bone marrow | hematopoietic stem cell | beta-thalassemia |
| E_00762 | chr8:128044721-128046192 | blood | malignant cell | NA |
| E_00802 | chr8:128044721-128046192 | blood | malignant cell | NA |
| E_00763 | chr8:128048231-128050347 | blood | malignant cell | NA |
| E_00803 | chr8:128048231-128050347 | blood | malignant cell | NA |
| E_02496 | chr8:128172101-128172473 | lymph node | germinal center B cell | diffuse large B-cell lymphoma |
| E_02497 | chr8:128172101-128172473 | lymph node | germinal center B cell | diffuse large B-cell lymphoma |
| E_02498 | chr8:128172101-128172473 | lymph node | germinal center B cell | diffuse large B-cell lymphoma |
| E_02499 | chr8:128172101-128172473 | ascitic fluid | germinal center B cell | diffuse large B-cell lymphoma |
| E_02500 | chr8:128172101-128172473 | ascitic fluid | germinal center B cell | diffuse large B-cell lymphoma |
| E_02501 | chr8:128172101-128172473 | ascitic fluid | germinal center B cell | diffuse large B-cell lymphoma |
| E_02572 | chr8:128172101-128172473 | inguinal part of abdomen | B cell | diffuse large B-cell lymphoma |
| E_00836 | chr8:128264000-128277000 | blood | plasma cell | plasma cell myeloma |
| E_00837 | chr8:128264000-128277000 | blood | plasma cell | plasma cell myeloma |
| E_02018 | chr8:128554145-128555945 | liver | hepatocyte | hepatocellular carcinoma |
| E_02113 | chr8:128556059-128557653 | liver | malignant cell | hepatocellular carcinoma |
| E_04547 | chr8:128600697-128601159 | uterine cervix | malignant cell | prostate cancer |
| E_04548 | chr8:128600697-128601159 | uterine cervix | malignant cell | prostate cancer |
| E_03680 | chr8:128740000-128750000 | blood | malignant cell | myeloid malignancy |
| E_03681 | chr8:128740000-128750000 | blood | malignant cell | myeloid malignancy |
| E_03062 | chr8:128747000-128748000 | blood | malignant cell | NA |
| E_01176 | chr8:128804981-128806980 | colon | malignant cell | colorectal carcinoma |
| E_02299 | chr8:128840000-128890000 | kidney | malignant cell | rhabdoid tumor |
| E_02303 | chr8:129440000-129740000 | kidney | malignant cell | rhabdoid tumor |
| E_00764 | chr8:129581780-129583797 | blood | malignant cell | NA |
| E_00804 | chr8:129581780-129583797 | blood | malignant cell | NA |
| E_00057 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00058 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00059 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00060 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00061 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00062 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00161 | chr8:129582024-129582425 | bone marrow | malignant cell | acute myeloid leukemia with t(3; 8)(q26; q24) MECOM rearrangement |
| E_00162 | chr8:129582024-129582425 | blood | malignant cell | acute myeloid leukemia |
| E_00163 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00164 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00165 | chr8:129582024-129582425 | bone marrow | malignant cell | acute myeloid leukemia with t(3; 8)(q26; q24) MECOM rearrangement |
| E_00166 | chr8:129582024-129582425 | blood | malignant cell | acute myeloid leukemia |
| E_00167 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00168 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00169 | chr8:129582024-129582425 | bone marrow | malignant cell | acute myeloid leukemia with t(3; 8)(q26; q24) MECOM rearrangement |
| E_00170 | chr8:129582024-129582425 | blood | malignant cell | acute myeloid leukemia |
| E_00171 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00172 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00173 | chr8:129582024-129582425 | bone marrow | malignant cell | acute myeloid leukemia with t(3; 8)(q26; q24) MECOM rearrangement |
| E_00174 | chr8:129582024-129582425 | blood | malignant cell | acute myeloid leukemia |
| E_00175 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00176 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00177 | chr8:129582024-129582425 | bone marrow | malignant cell | acute myeloid leukemia with t(3; 8)(q26; q24) MECOM rearrangement |
| E_00178 | chr8:129582024-129582425 | blood | malignant cell | acute myeloid leukemia |
| E_00179 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00180 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00181 | chr8:129582024-129582425 | bone marrow | malignant cell | acute myeloid leukemia with t(3; 8)(q26; q24) MECOM rearrangement |
| E_00182 | chr8:129582024-129582425 | blood | malignant cell | acute myeloid leukemia |
| E_00183 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00184 | chr8:129582024-129582425 | bone marrow | myeloid leukemia blast cell | acute myeloid leukemia |
| E_00247 | chr8:129582024-129582425 | blood | CD34-positive hematopoietic stem/progenitor cell | NA |
| E_00248 | chr8:129582024-129582425 | blood | CD34-positive hematopoietic stem/progenitor cell | NA |
| E_00249 | chr8:129582024-129582425 | blood | CD34-positive hematopoietic stem/progenitor cell | NA |
| E_00250 | chr8:129582024-129582425 | blood | CD34-positive hematopoietic stem/progenitor cell | NA |
| E_00251 | chr8:129582024-129582425 | blood | CD34-positive hematopoietic stem/progenitor cell | NA |
| E_00252 | chr8:129582024-129582425 | blood | CD34-positive hematopoietic stem/progenitor cell | NA |
| E_00398 | chr8:129582024-129582425 | bone marrow | myeloid leukemia cell | acute myeloid leukemia |
| E_00399 | chr8:129582024-129582425 | blood | myeloid leukemia cell | acute myeloid leukemia |
Expression of Target Genes for the Enhancer