About Enhancer
| Enhancer ID: | E_03882 |
| Species: | Homo sapiens |
| Position : | chr7:117075514-117075933   |
| Year: | 2015 |
| Title: | Oxidative stress regulates CFTR gene expression in human airway epithelial cells through a distal antioxidant response element. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 25259561 |
| Cell Source: | Human Bronchial Epithelial Cell |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; EMSA/gel-shift assay |
About Target Gene
| Target gene : | CFTR |
About TF
| TF name : | BACH1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| BACH1 | BARD1 signaling events | pid | 29 |
| BACH1 | Kaposi sarcoma-associated herpesvirus | mirtarbase | 13 |
| BACH1 | Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 | wikipathways | 122 |
| BACH1 | Hs_Integrated_Cancer_Pathway_WP1971_82939 | wikipathways | 33 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
9 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04477 | chr7:117074000-117077000 | nasal cavity epithelium | nasal epithelial cell | NA |
| E_00034 | chr7:117075400-117076000 | bronchus | bronchial epithelial cell | NA |
| E_00035 | chr7:117075400-117076000 | pleural effusion | epithelial cell | NA |
| E_00036 | chr7:117075400-117076000 | bronchus | bronchial epithelial cell | NA |
| E_00037 | chr7:117075400-117076000 | pleural effusion | epithelial cell | NA |
| E_00038 | chr7:117075400-117076000 | bronchus | bronchial epithelial cell | NA |
| E_00039 | chr7:117075400-117076000 | pleural effusion | epithelial cell | NA |
| E_03835 | chr7:117075400-117076000 | bronchus | bronchial epithelial cell | NA |
| E_03883 | chr7:117075514-117075933 | NA | NA | NA |
Expression of Target Genes for the Enhancer