About Enhancer
| Enhancer ID: | E_03894 |
| Species: | Homo sapiens |
| Position : | chr10:81115805-81116305   |
| Year: | 2021 |
| Title: | Genome-wide enhancer maps link risk variants to disease genes. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | inflammatory bowel disease |
| PMID: | 33828297 |
| MONDO: | MONDO:0005265 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | THP-1 |
| CVCL ID: | CVCL_0006 |
| Cell Type: | monocyte |
| Cell Ontology ID: | CL:0000576 |
| Experiment Type: | Enhancer-target functional validation; endogenous perturbation; downstream cellular phenotype; Disease-variant functional analysis |
| High Throughput Method: | ATAC-seq/DNase-seq; H3K27ac profiling; Hi-C; ABC enhancer-gene mapping; GWAS |
| Low Throughput Method: | CRISPRi-FlowFISH; PPIF expression analysis; MitoTracker mitochondrial membrane-potential assay |
About Target Gene
| Target gene : | PPIF |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer