About Enhancer
| Enhancer ID: | E_03945 |
| Species: | Homo sapiens |
| Position : | chr3:157437977-157438893   |
| Year: | 2023 |
| Title: | Mena regulates nesprin-2 to control actin-nuclear lamina associations, trans-nuclear membrane signalling and gene expression. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | skin squamous cell carcinoma |
| PMID: | 36959177 |
| MONDO: | MONDO:0002529 |
| Tissue: | zone of skin |
| Tissue Ontology ID: | UBERON:0000014 |
| Cell Source: | 293T human CD33 |
| CVCL ID: | CVCL_UE24 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | DamID-seq, RNA-seq |
| Low Throughput Method: | CRISPR Knockout, qRT-PCR |
About Target Gene
| Target gene : | PTX3 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Repressed |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer