About Enhancer
| Enhancer ID: | E_03958 |
| Species: | Homo sapiens |
| Position : | chr17:45436112-45436891   |
| Year: | 2020 |
| Title: | BCL9/STAT3 regulation of transcriptional enhancer networks promote DCIS progression. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | breast cancer |
| PMID: | 32352029 |
| MONDO: | MONDO:0007254 |
| Tissue: | breast |
| Tissue Ontology ID: | UBERON:0000310 |
| Cell Source: | 293T human CLDN18.2 |
| CVCL ID: | CVCL_UE18 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay; In vivo functional validation |
| High Throughput Method: | ChIP-exo, RNA-seq, RPPA; RNA-seq |
| Low Throughput Method: | ChIP-qPCR, shRNA Knockdown, RT-qPCR, Western blot, In vivo Invasion Assay; ChIP; In vivo phenotyping |
About Target Gene
| Target gene : | ITGB3 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer