About Enhancer
| Enhancer ID: | E_03963 |
| Species: | Mus musculus |
| Position : | chr19:61151074-61161722   |
| Year: | 2018 |
| Title: | Transcription Factor IRF8 Governs Enhancer Landscape Dynamics in Mononuclear Phagocyte Progenitors. |
| Genome Build: | mm10 |
| Enhancer Type: | Super-enhancer |
| Condition: | Normal |
| PMID: | 29514092 |
| Cell Source: | Monocytes,Dendritic Cells |
| Cell Type: | monocyte |
| Cell Ontology ID: | CL:0000576 |
| Experiment Type: | TF-binding/chromatin assay; In vivo functional validation |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | ChIP-qPCR/ChIP; RT-qPCR/qPCR; Transgenic/LacZ assay |
About Target Gene
| Target gene : | Csf2ra |
About TF
| TF name : | Irf8 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Irf8 | GMCSF-mediated signaling events | pid | 38 |
| Irf8 | Interferon alpha/beta signaling | reactome | 67 |
| Irf8 | Interferon gamma signaling | reactome | 88 |
| Irf8 | Validated targets of C-MYC transcriptional repression | pid | 63 |
| Irf8 | Hs_Type_II_interferon_signaling_(IFNG)_WP619_71168 | wikipathways | 10 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03964 | chr19:61158643-61164569 | NA | monocyte | NA |
Expression of Target Genes for the Enhancer