Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03971
Species: Mus musculus
Position : chr3:127641624-127642545
Year: 2015
Title: Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  25804738
Tissue: brain
Tissue Ontology ID: UBERON:0000955
Cell Source: Embryonic Stem Cell
Experiment Type: TF-binding/chromatin assay; In vivo functional validation
High Throughput Method: ChIP-seq; RNA-seq
Low Throughput Method: ChIP-qPCR/ChIP; RT-qPCR/qPCR; Transgenic/LacZ assay
About Target Gene
Target gene : Neurog2
About TF
TF name : Foxa1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Foxa1 AndrogenReceptor netpath 167
Foxa1 Direct p53 effectors pid 141
Foxa1 FOXA1 transcription factor network pid 45
Foxa1 FOXA2 and FOXA3 transcription factor networks pid 45
Foxa1 Hs_Endoderm_Differentiation_WP2853_88152 wikipathways 62
Enhancer Associated Network
Overlapping Enhancers (mm10) 2 found
Enhancer ID Position Tissue Cell Disease
E_03972 chr3:127641624-127642545 brain NA NA
E_03973 chr3:127641624-127642545 brain NA NA
Expression of Target Genes for the Enhancer