About Enhancer
| Enhancer ID: | E_03972 |
| Species: | Mus musculus |
| Position : | chr3:127641624-127642545   |
| Year: | 2015 |
| Title: | Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 25804738 |
| Tissue: | brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | Embryonic Stem Cell |
| Experiment Type: | TF-binding/chromatin assay; In vivo functional validation |
| High Throughput Method: | ChIP-seq; RNA-seq |
| Low Throughput Method: | ChIP-qPCR/ChIP; RT-qPCR/qPCR; Transgenic/LacZ assay |
About Target Gene
| Target gene : | Neurog2 |
About TF
| TF name : | Foxa2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Foxa2 | FOXA1 transcription factor network | pid | 45 |
| Foxa2 | FOXA2 and FOXA3 transcription factor networks | pid | 45 |
| Foxa2 | Hedgehog signaling events mediated by Gli proteins | pid | 49 |
| Foxa2 | Regulation of gene expression in beta cells | reactome | 17 |
| Foxa2 | Maturity onset diabetes of the young | kegg | 25 |
| Foxa2 | Hs_Endoderm_Differentiation_WP2853_88152 | wikipathways | 62 |
| Foxa2 | Hs_Dopaminergic_Neurogenesis_WP2855_87239 | wikipathways | 19 |
| Foxa2 | Hs_Heart_Development_WP1591_90186 | wikipathways | 28 |
| Foxa2 | Hs_Ectoderm_Differentiation_WP2858_89329 | wikipathways | 56 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer