About Enhancer
| Enhancer ID: | E_03999 |
| Species: | Homo sapiens |
| Position : | chr9:128335472-128336978   |
| Year: | 2020 |
| Title: | Genetic Predisposition to Glioma Mediated by a MAPKAP1 Enhancer Variant. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | glioma |
| PMID: | 31773361 |
| MONDO: | MONDO:0021042 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Lymphoblastoid cell line |
| Cell Type: | lymphoblast |
| Cell Ontology ID: | CL:0017005 |
| Experiment Type: | Enhancer activity assay; TF binding assay; Functional perturbation assay |
| Low Throughput Method: | Luciferase Reporter Assay; EMSA; ChIP-qPCR; RT-qPCR |
About Target Gene
| Target gene : | MAPKAP1 |
About TF
| TF name : | NFIC |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| NFIC | FOXA1 transcription factor network | pid | 45 |
| NFIC | p75(NTR)-mediated signaling | pid | 74 |
| NFIC | RNA Polymerase III Abortive And Retractive Initiation | reactome | 41 |
| NFIC | RNA Polymerase III Transcription Termination | reactome | 23 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04010 | chr9:128335472-128336978 | brain | glioma cell | glioma |
Expression of Target Genes for the Enhancer