About Enhancer
| Enhancer ID: | E_04005 |
| Species: | Homo sapiens |
| Position : | chr2:60447611-60449611   |
| Year: | 2019 |
| Title: | Expression analysis data of BCL11A and 污-globin genes in KU812 and KG-1?cell lines after CRISPR/Cas9-mediated BCL11A enhancer deletion. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | beta-thalassemia |
| PMID: | 31890812 |
| MONDO: | MONDO:0019402 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | KG-1 |
| Cell Type: | erythroid/myeloid leukemia cell line used for BCL11A enhancer editing |
| Experiment Type: | Enhancer CRISPR perturbation study, Chromatin interaction assay; Endogenous enhancer perturbation |
| Low Throughput Method: | 3C, RT-RT-qPCR; CRISPR-Cas9 endogenous deletion/editing |
About Target Gene
| Target gene : | BCL11A |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04006 | chr2:60447611-60449611 | blood | erythroid/myeloid leukemia cell line used for BCL11A enhancer editing | beta-thalassemia |
Expression of Target Genes for the Enhancer