About Enhancer
| Enhancer ID: | E_04012 |
| Species: | Homo sapiens |
| Position : | chr21:40000000-40800000   |
| Year: | 2024 |
| Title: | SMC3 contributes to heart development by regulating super-enhancer associated genes. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 39085358 |
| Tissue: | heart |
| Tissue Ontology ID: | UBERON:0000948 |
| Cell Source: | Cardiomyocytes |
| Cell Type: | cardiac muscle cell |
| Cell Ontology ID: | CL:0000746 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay; Endogenous enhancer perturbation; Disease-variant functional analysis; In vivo functional validation |
| High Throughput Method: | Hi-C, ChIP-seq; RNA-seq |
| Low Throughput Method: | qRT-PCR, and ChIP-qPCR; Mouse genetic deletion/knock-in |
About Target Gene
| Target gene : | ETS2 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
3 found
Expression of Target Genes for the Enhancer