Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04015
Species: Mus musculus
Position : chr10:72894616-72895600
Year: 2020
Title: The Atoh7 remote enhancer provides transcriptional robustness during retinal ganglion cell development.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  32817515
Tissue: retina
Tissue Ontology ID: UBERON:0000966
Cell Source: developing retina
Cell Type: retinal ganglion cell
Cell Ontology ID: CL:0000740
Experiment Type: Enhancer activity assay; Endogenous enhancer perturbation; In vivo functional validation
High Throughput Method: ATAC-seq
Low Throughput Method: Transgenic reporter assay; CRISPR/Cas9 deletion; RT-PCR; Immunostaining; CRISPR-Cas9 endogenous deletion/editing; Mouse genetic deletion/knock-in
About Target Gene
Target gene : Atoh7
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 2 found
Enhancer ID Position Tissue Cell Disease
E_04020 chr10:72890000-72895600 retina retinal progenitor cell NA
E_04021 chr10:72890000-72895600 retina retinal ganglion cell NA
Expression of Target Genes for the Enhancer