About Enhancer
| Enhancer ID: | E_04021 |
| Species: | Mus musculus |
| Position : | chr10:72890000-72895600   |
| Year: | 2020 |
| Title: | The Atoh7 remote enhancer provides transcriptional robustness during retinal ganglion cell development. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 32817515 |
| Tissue: | retina |
| Tissue Ontology ID: | UBERON:0000966 |
| Cell Source: | Retinal Ganglion Cells |
| Cell Type: | retinal ganglion cell |
| Cell Ontology ID: | CL:0000740 |
| Experiment Type: | Enhancer deletion assay; In vivo developmental assay; Enhancer activity assay |
| High Throughput Method: | ATAC-seq; RNA-seq; ChIP-seq |
| Low Throughput Method: | Genome editing of remote enhancer; RT-qPCR; immunostaining; optic-nerve and retinal phenotyping |
About Target Gene
| Target gene : | Atoh7 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
4 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04013 | chr10:72890000-72890392 | retina | retinal progenitor cell | NA |
| E_04014 | chr10:72890000-72890392 | retina | retinal ganglion cell | NA |
| E_04020 | chr10:72890000-72895600 | retina | retinal progenitor cell | NA |
| E_04015 | chr10:72894616-72895600 | retina | retinal ganglion cell | NA |
Expression of Target Genes for the Enhancer