About Enhancer
| Enhancer ID: | E_04028 |
| Species: | Mus musculus |
| Position : | chr16:95745432-95912361   |
| Year: | 2024 |
| Title: | SMC3 contributes to heart development by regulating super-enhancer associated genes. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 39085358 |
| Tissue: | heart |
| Tissue Ontology ID: | UBERON:0000948 |
| Cell Source: | Outflow tract cardiac muscle cells |
| Cell Type: | cardiac muscle cell |
| Cell Ontology ID: | CL:0000746 |
| Experiment Type: | Functional perturbation assay, Enhancer activity assay; Endogenous enhancer perturbation; Disease-variant functional analysis; In vivo functional validation |
| High Throughput Method: | ChIP-seq, RNA-seq, snRNA-seq; RNA-seq |
| Low Throughput Method: | CRISPR Knockout, RT-RT-qPCR, Western blot, H&E Staining; Mouse genetic deletion/knock-in |
About Target Gene
| Target gene : | Ets2 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Repressed |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer