Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04039
Species: Mus musculus
Position : chr5:29314591-29316266
Year: 2022
Title: Etv2 regulates enhancer chromatin status to initiate Shh expression in the limb bud.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  35864091
Tissue: limb bud
Tissue Ontology ID: UBERON:0004347
Cell Source: Embryonic limb mesenchyme
Cell Type: limb mesenchyme cell
Experiment Type: Enhancer activity assay, TF binding assay, Chromatin interaction assay
High Throughput Method: ATAC-seq; ChIP-seq
Low Throughput Method: Luciferase Reporter Assay; ChIP-RT-qPCR; EMSA
About Target Gene
Target gene : Shh
About TF
TF name : Etv2
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 4 found
Enhancer ID Position Tissue Cell Disease
E_04542 chr5:29314497-29315862 limb bud embryonic stem cell NA
E_00900 chr5:29314881-29315667 limb bud mesenchymal cell NA
E_00901 chr5:29314881-29315667 limb bud mesenchymal cell NA
E_00902 chr5:29314881-29315667 limb bud mesenchymal cell NA
Expression of Target Genes for the Enhancer