About Enhancer
| Enhancer ID: | E_04049 |
| Species: | Homo sapiens |
| Position : | chr14:106328838-106329184   |
| Year: | 2024 |
| Title: | Core regions in immunoglobulin heavy chain enhancers essential for survival of non-Hodgkin lymphoma cells are identified by a CRISPR interference screen. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Burkitt lymphoma |
| PMID: | 38934080 |
| MONDO: | MONDO:0007243 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Human Burkitt lymphoma cell |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Functional perturbation assay, Enhancer activity assay; Endogenous enhancer perturbation |
| High Throughput Method: | CRISPRi screening, RNA-seq, ATAC-seq; RNA-seq; CRISPR genetic screen |
| Low Throughput Method: | CRISPRi, RT-RT-qPCR, Western blot, Flow Cytometry, GFP competition assay; CRISPRi |
About Target Gene
| Target gene : | IGH |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_05180 | chr14:106327635-106328903 | NA | B cell | NA |
Expression of Target Genes for the Enhancer