About Enhancer
| Enhancer ID: | E_04061 |
| Species: | Mus musculus |
| Position : | chr17:26850487-26850997   |
| Year: | 2016 |
| Title: | Desmin enters the nucleus of cardiac stem cells and modulates Nkx2.5 expression by participating in transcription factor complexes that interact with the nkx2.5 gene. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 26787680 |
| Tissue: | heart |
| Tissue Ontology ID: | UBERON:0000948 |
| Cell Source: | Cardiac progenitor cells from differentiating embryoid bodies |
| Cell Type: | cardiac muscle myoblast |
| Cell Ontology ID: | CL:0000513 |
| Experiment Type: | Enhancer activity assay; Chromatin occupancy assay; Functional perturbation assay |
| Low Throughput Method: | Luciferase Reporter Assay; ChIP-PCR/ChIP-qPCR; Desmin knockdown/overexpression; RT-qPCR; Western blot; Co-immunoprecipitation |
About Target Gene
| Target gene : | Nkx2-5 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer