About Enhancer
| Enhancer ID: | E_04075 |
| Species: | Homo sapiens |
| Position : | chr6:132200000-132202000   |
| Year: | 2020 |
| Title: | Highly interconnected enhancer communities control lineage-determining genes in human mesenchymal stem cells. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 33020665 |
| Tissue: | bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | bone marrow mesenchymal stem |
| Cell Type: | mesenchymal stem cell |
| Cell Ontology ID: | CL:0000134 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, TF binding assay |
| High Throughput Method: | ECHi-C, ChIP-seq, scATAC-seq, scRNA-seq, RNA-seq |
| Low Throughput Method: | ChIP-RT-qPCR, RT-RT-qPCR |
About Target Gene
| Target gene : | CCN2 |
About TF
| TF name : | TEAD4 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| TEAD4 | PPARA activates gene expression | reactome | 113 |
| TEAD4 | YAP1- and WWTR1 (TAZ)-stimulated gene expression | reactome | 29 |
| TEAD4 | Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 | wikipathways | 153 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04074 | chr6:132200000-132202000 | bone marrow | mesenchymal stem cell | NA |
Expression of Target Genes for the Enhancer