About Enhancer
| Enhancer ID: | E_04095 |
| Species: | Homo sapiens |
| Position : | chr14:106041116-106041795   |
| Year: | 2024 |
| Title: | Core regions in immunoglobulin heavy chain enhancers essential for survival of non-Hodgkin lymphoma cells are identified by a CRISPR interference screen. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Burkitt lymphoma |
| PMID: | 38934080 |
| MONDO: | MONDO:0007243 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Diffuse large B-cell lymphoma cell line |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Functional perturbation assay; Endogenous enhancer perturbation |
| High Throughput Method: | CRISPR screen; RNA-seq; CRISPR genetic screen |
| Low Throughput Method: | RT-RT-qPCR, Western blot; CRISPRi |
About Target Gene
| Target gene : | BCL2 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer