About Enhancer
| Enhancer ID: | E_04104 |
| Species: | Homo sapiens |
| Position : | chr11:111152290-111154290   |
| Year: | 2014 |
| Title: | Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q23.1. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | colorectal carcinoma |
| PMID: | 24256810 |
| MONDO: | MONDO:0024331 |
| Tissue: | colon |
| Tissue Ontology ID: | UBERON:0001155 |
| Cell Source: | HCT 116 |
| CVCL ID: | CVCL_0291 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | GWAS fine-mapping; allele-specific enhancer validation; candidate target association |
| High Throughput Method: | H3K4me1 ChIP-seq; DNase-seq/ENCODE integration; genetic association; ChIP-seq; eQTL analysis |
| Low Throughput Method: | Luciferase reporter; EMSA; eQTL/expression analysis |
About Target Gene
| Target gene : | COLCA1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
10 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04076 | chr11:111150916-111155431 | colon | malignant cell | colorectal cancer |
| E_04077 | chr11:111150916-111155431 | colon | malignant cell | colorectal cancer |
| E_04122 | chr11:111150916-111155431 | colon | malignant cell | colorectal cancer |
| E_04092 | chr11:111152290-111154290 | colon | epithelial cell | colorectal cancer |
| E_04093 | chr11:111152290-111154290 | colon | epithelial cell | colorectal cancer |
| E_04102 | chr11:111152290-111154290 | colon | malignant cell | colorectal carcinoma |
| E_04103 | chr11:111152290-111154290 | colon | malignant cell | colorectal carcinoma |
| E_04105 | chr11:111152290-111154290 | colon | malignant cell | colorectal carcinoma |
| E_04106 | chr11:111152290-111154290 | colon | malignant cell | colorectal carcinoma |
| E_04107 | chr11:111152290-111154290 | colon | malignant cell | colorectal carcinoma |
Expression of Target Genes for the Enhancer