Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04122
Species: Homo sapiens
Position : chr11:111150916-111155431
Year: 2014
Title: Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q23.1.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: colorectal cancer
PMID:  24256810
MONDO: MONDO:0005575
Tissue: colon
Tissue Ontology ID: UBERON:0001155
Cell Source: HCT 116,SW480,Colorectal Cancer
CVCL ID: CVCL_0291
Cell Type: malignant cell
Cell Ontology ID: CL:0001064
Experiment Type: Enhancer activity assay; TF-binding/chromatin assay; Genetic-variant functional analysis; Disease-associated enhancer analysis
High Throughput Method: ChIP-seq
Low Throughput Method: Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; EMSA/gel-shift assay
About Target Gene
Target gene : POU2AF2
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 10 found
Enhancer ID Position Tissue Cell Disease
E_04076 chr11:111150916-111155431 colon malignant cell colorectal cancer
E_04077 chr11:111150916-111155431 colon malignant cell colorectal cancer
E_04092 chr11:111152290-111154290 colon epithelial cell colorectal cancer
E_04093 chr11:111152290-111154290 colon epithelial cell colorectal cancer
E_04102 chr11:111152290-111154290 colon malignant cell colorectal carcinoma
E_04103 chr11:111152290-111154290 colon malignant cell colorectal carcinoma
E_04104 chr11:111152290-111154290 colon malignant cell colorectal carcinoma
E_04105 chr11:111152290-111154290 colon malignant cell colorectal carcinoma
E_04106 chr11:111152290-111154290 colon malignant cell colorectal carcinoma
E_04107 chr11:111152290-111154290 colon malignant cell colorectal carcinoma
Expression of Target Genes for the Enhancer