Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04142
Species: Homo sapiens
Position : chr16:86178434-86238313
Year: 2022
Title: Ultra-conserved non-coding sequences within the FOXF1 enhancer are critical for human lung development.
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
PMID:  36157490
Tissue: lung
Tissue Ontology ID: UBERON:0002048
Cell Source: IMR-90
CVCL ID: CVCL_0347
Cell Type: fibroblast
Cell Ontology ID: CL:0000057
Experiment Type: Enhancer activity assay; Coactivator binding assay; Functional perturbation assay; DNA methylation assay
High Throughput Method: Genome sequencing; ChIP-seq (ENCODE/public-data analysis)
Low Throughput Method: Dual-Luciferase Reporter Assay; siRNA Knockdown; RT-qPCR; LINC01082 Overexpression; Methylation-sensitive Restriction Digestion
About Target Gene
Target gene : FOXF1
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 1 found
Enhancer ID Position Tissue Cell Disease
E_04161 chr16:86194740-86195815 lung fetal lung fibroblast NA
Expression of Target Genes for the Enhancer