About Enhancer
| Enhancer ID: | E_04151 |
| Species: | Homo sapiens |
| Position : | chr2:8818311-8820522   |
| Year: | 2018 |
| Title: | Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | neuroblastoma |
| PMID: | 29379199 |
| MONDO: | MONDO:0005072 |
| Cell Source: | Neuroblastoma Cell Lines |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | TF-binding/chromatin assay; In vivo functional validation; Disease-associated enhancer analysis |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | ChIP-qPCR/ChIP; Western blot |
About Target Gene
| Target gene : | ID2 |
About TF
| TF name : | MYCN |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| MYCN | Hs_Pathways_Affected_in_Adenoid_Cystic_Carcinoma_WP3651_89271 | wikipathways | 27 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer