Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04173
Species: Mus musculus
Position : chr1:182851627-182852853
Year: 2014
Title: 5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  25263596
Cell Source: Tet2-/-
Experiment Type: TF-binding/chromatin assay; In vivo functional validation
High Throughput Method: ChIP-seq
Low Throughput Method: ChIP-qPCR/ChIP; Transgenic/LacZ assay
About Target Gene
Target gene : Lefty1
About TF
TF name : Sox4
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Sox4 Deactivation of the beta-catenin transactivating complex reactome 42
Sox4 IL5 netpath 59
Enhancer Associated Network
Overlapping Enhancers (mm10) 5 found
Enhancer ID Position Tissue Cell Disease
E_04171 chr1:182851627-182852853 NA NA NA
E_04172 chr1:182851627-182852853 NA NA NA
E_04174 chr1:182852133-182854320 NA NA NA
E_04175 chr1:182852133-182854320 NA NA NA
E_04176 chr1:182852133-182854320 NA NA NA
Expression of Target Genes for the Enhancer