Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04211
Species: Homo sapiens
Position : chr4:174441057-174442400
Year: 2018
Title: Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: neuroblastoma
PMID:  29379199
MONDO: MONDO:0005072
Cell Source: Neuroblastoma Cell Lines
Cell Type: malignant cell
Cell Ontology ID: CL:0001064
Experiment Type: TF-binding/chromatin assay; Disease-associated enhancer analysis
High Throughput Method: ChIP-seq
Low Throughput Method: ChIP-qPCR/ChIP; Western blot
About Target Gene
Target gene : HAND2
About TF
TF name : MYCN
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
MYCN Hs_Pathways_Affected_in_Adenoid_Cystic_Carcinoma_WP3651_89271 wikipathways 27
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer