About Enhancer
| Enhancer ID: | E_04220 |
| Species: | Mus musculus |
| Position : | chr8:57331591-57335031   |
| Year: | 2023 |
| Title: | The NR2F2-HAND2 signaling axis regulates progesterone actions in the uterus at early pregnancy |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 37664846 |
| Tissue: | uterus |
| Tissue Ontology ID: | UBERON:0000995 |
| Cell Source: | GD3.5 pregnant mouse uterus / uterine stromal cells |
| Cell Type: | endometrial stromal cell |
| Experiment Type: | TF binding assay; enhancer chromatin-state mapping; conditional TF perturbation; enhancer orthology/functional validation |
| High Throughput Method: | NR2F2 ChIP-seq; RNA-seq |
| Low Throughput Method: | ChIP-qPCR; RT-qPCR; conditional Nr2f2 knockout phenotyping; Western blot |
About Target Gene
| Target gene : | Hand2 |
About TF
| TF name : | Nr2f2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Nr2f2 | FOXA1 transcription factor network | pid | 45 |
| Nr2f2 | Regulation of Telomerase | pid | 70 |
| Nr2f2 | Transcriptional regulation of white adipocyte differentiation | reactome | 79 |
| Nr2f2 | Hs_White_fat_cell_differentiation_WP3946_90940 | wikipathways | 30 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer