About Enhancer
| Enhancer ID: | E_04222 |
| Species: | Mus musculus |
| Position : | chr6:115566900-115569800   |
| Year: | 2020 |
| Title: | NFIA differentially controls adipogenic and myogenic gene program through distinct pathways to ensure brown and beige adipocyte differentiation. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 32991581 |
| Tissue: | adipose tissue |
| Tissue Ontology ID: | UBERON:0001013 |
| Cell Source: | C2C12 |
| CVCL ID: | CVCL_0188 |
| Cell Type: | mouse myoblast cell line |
| Experiment Type: | Enhancer activity assay; TF binding assay; Functional perturbation assay |
| High Throughput Method: | ChIP-seq; FAIRE-seq; RNA-seq |
| Low Throughput Method: | ChIP-qPCR; FAIRE-qPCR; CRISPR-dCas9-KRAB; RT-qPCR |
About Target Gene
| Target gene : | Pparg |
About TF
| TF name : | Nfia |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Nfia | FOXA1 transcription factor network | pid | 45 |
| Nfia | RNA Polymerase III Abortive And Retractive Initiation | reactome | 41 |
| Nfia | RNA Polymerase III Transcription Termination | reactome | 23 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer