About Enhancer
| Enhancer ID: | E_04226 |
| Species: | Mus musculus |
| Position : | chr6:52199038-52200503   |
| Year: | 2014 |
| Title: | YY1 acts as a transcriptional activator of Hoxa5 gene expression in mouse organogenesis. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 24705708 |
| Tissue: | lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | Lung,Stomach |
| Experiment Type: | TF-binding/chromatin assay; In vivo functional validation |
| Low Throughput Method: | ChIP-qPCR/ChIP; EMSA/gel-shift assay; RT-qPCR/qPCR; Transgenic/LacZ assay |
About Target Gene
| Target gene : | Vegfa |
About TF
| TF name : | Yy1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Yy1 | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| Yy1 | DNA Damage Recognition in GG-NER | reactome | 38 |
| Yy1 | E2F transcription factor network | pid | 77 |
| Yy1 | mTOR signaling pathway | pid | 66 |
| Yy1 | Notch-mediated HES/HEY network | pid | 48 |
| Yy1 | Notch | netpath | 76 |
| Yy1 | Notch signaling pathway | pid | 58 |
| Yy1 | p53 pathway | pid | 59 |
| Yy1 | Signaling events mediated by HDAC Class I | pid | 89 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer