About Enhancer
| Enhancer ID: | E_04235 |
| Species: | Homo sapiens |
| Position : | chr2:12600000-12649999   |
| Year: | 2020 |
| Title: | Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | neuroblastoma |
| PMID: | 33199677 |
| MONDO: | MONDO:0005072 |
| Tissue: | adrenal gland |
| Tissue Ontology ID: | UBERON:0002369 |
| Cell Source: | IMR-5/75 |
| CVCL ID: | CVCL_M473 |
| Cell Type: | neuroblastoma cell |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay |
| High Throughput Method: | ChIP-seq; RNA-seq; ATAC-seq; Hi-C; Oxford Nanopore sequencing |
| Low Throughput Method: | qRT-PCR, and ChIP-qPCR |
About Target Gene
| Target gene : | MYCN |
About TF
| TF name : | HAND2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| HAND2 | Hs_Heart_Development_WP1591_90186 | wikipathways | 28 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer