About Enhancer
| Enhancer ID: | E_04243 |
| Species: | Homo sapiens |
| Position : | chr7:117504671-117505671   |
| Year: | 2022 |
| Title: | Epigenome editing of the CFTR-locus for treatment of cystic fibrosis. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 34049825 |
| Tissue: | kidney |
| Tissue Ontology ID: | UBERON:0002113 |
| Cell Source: | HEK293T |
| CVCL ID: | CVCL_0063 |
| Cell Type: | embryonic kidney cell |
| Experiment Type: | Functional perturbation assay |
| Low Throughput Method: | CRISPR Knockout; CRISPRi; RT-RT-qPCR; Western blot; Ussing Chamber Assay |
About Target Gene
| Target gene : | CFTR |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04251 | chr7:117504671-117505671 | lung | bronchial epithelial cell | cystic fibrosis |
Expression of Target Genes for the Enhancer