About Enhancer
| Enhancer ID: | E_04249 |
| Species: | Homo sapiens |
| Position : | chr8:127247950-127248600   |
| Year: | 2025 |
| Title: | Dynamic interaction of MYC enhancer RNA with YEATS2 protein regulates MYC gene transcription in pancreatic cancer. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | pancreatic ductal adenocarcinoma |
| PMID: | 40216980 |
| MONDO: | MONDO:0005184 |
| Tissue: | pancreas |
| Tissue Ontology ID: | UBERON:0001264 |
| Cell Source: | AsPC-1 |
| CVCL ID: | CVCL_0152 |
| Cell Type: | pancreatic ductal cell |
| Cell Ontology ID: | CL:0002079 |
| Experiment Type: | Enhancer/eRNA expression validation; RNA-protein interaction assay; Chromatin occupancy assay |
| Low Throughput Method: | RT-qPCR; UV-RIP-qPCR; ZZZ3 ChIP-qPCR; YEATS2 immunoprecipitation; Phosphotyrosine Western blot; TNF-alpha stimulation |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer