About Enhancer
| Enhancer ID: | E_04252 |
| Species: | Homo sapiens |
| Position : | chr11:5288664-5288684   |
| Year: | 1990 |
| Title: | Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 2116990 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | erythroblast |
| Cell Ontology ID: | CL:0000765 |
| Experiment Type: | Enhancer activity assay; cis-element functional mapping; TF-complex binding assay |
| Low Throughput Method: | Reporter assay; DNA-protein binding assay; AP-1-site mutagenesis; erythroid induction assay |
About Target Gene
| Target gene : | HBE1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
7 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02356 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02363 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02364 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02365 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_04247 | chr11:5288664-5288684 | blood / hematopoietic system | erythroid progenitor cell | NA |
| E_04248 | chr11:5288664-5288684 | blood / hematopoietic system | malignant cell | NA |
| E_04250 | chr11:5288664-5288684 | blood | erythroid cell | NA |
Expression of Target Genes for the Enhancer