About Enhancer
| Enhancer ID: | E_04256 |
| Species: | Mus musculus |
| Position : | chr2:152735054-152735521   |
| Year: | 2016 |
| Title: | BMP Sustains Embryonic Stem Cell Self-Renewal through Distinct Functions of Different Kr邦ppel-like Factors. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 26771354 |
| Cell Source: | Embryonic Stem Cell |
| Experiment Type: | TF-binding/chromatin assay; Endogenous enhancer perturbation |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | ChIP-qPCR/ChIP; RT-qPCR/qPCR |
About Target Gene
| Target gene : | Id1 |
About TF
| TF name : | Smad5 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Smad5 | ALK1 signaling events | pid | 26 |
| Smad5 | ALK2 signaling events | pid | 11 |
| Smad5 | BMP receptor signaling | pid | 42 |
| Smad5 | BMP signaling pathway ( TGF-beta_BMP Diagram(MolecularVariation) ) | inoh | 34 |
| Smad5 | Gene expression of smad6/7 by R-smad:smad4 ( TGF-beta_super_family_signaling_pathway(canonical) ) | inoh | 8 |
| Smad5 | Gene expression of smad7 by R-smad:smad4 ( TGF-beta_super_family_signaling_pathway(canonical) ) | inoh | 7 |
| Smad5 | Kaposi sarcoma-associated herpesvirus | mirtarbase | 13 |
| Smad5 | Negative regulation of (transcription by R-smad:smad4) in TGF beta super family signaling pathway ( TGF-beta_super_family_signaling_pathway(canonical) ) | inoh | 21 |
| Smad5 | Signaling by BMP | reactome | 23 |
| Smad5 | TGF-beta signaling pathway | panther | 88 |
| Smad5 | TGF-beta_super_family_signaling_pathway(canonical) ( TGF-beta_BMP Diagram(MolecularVariation) ) | inoh | 51 |
| Smad5 | Wnt signaling pathway | panther | 250 |
| Smad5 | TGF-beta signaling pathway | kegg | 82 |
| Smad5 | Hs_Steroid_Biosynthesis_WP496_69016 | wikipathways | 8 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04255 | chr2:152735054-152735521 | NA | NA | NA |
Expression of Target Genes for the Enhancer