About Enhancer
| Enhancer ID: | E_04259 |
| Species: | Mus musculus |
| Position : | chr14:47056226-47056692   |
| Year: | 2012 |
| Title: | An evolutionarily conserved enhancer regulates Bmp4 expression in developing incisor and limb bud. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 22701669 |
| Cell Source: | LS-8 Cells |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; In vivo functional validation |
| Low Throughput Method: | ChIP-qPCR/ChIP; EMSA/gel-shift assay; RT-qPCR/qPCR |
About Target Gene
| Target gene : | Bmp4 |
About TF
| TF name : | Pitx2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Pitx2 | Regulation of nuclear beta catenin signaling and target gene transcription | pid | 80 |
| Pitx2 | TGF-beta signaling pathway | kegg | 82 |
| Pitx2 | Hs_Heart_Development_WP1591_90186 | wikipathways | 28 |
| Pitx2 | Hs_BMP_Signaling_Pathway_in_Eyelid_Development_WP3927_90735 | wikipathways | 11 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer