About Enhancer
| Enhancer ID: | E_04304 |
| Species: | Mus musculus |
| Position : | chr6:70546000-70546100   |
| Year: | 2005 |
| Title: | Long-range interactions between three transcriptional enhancers, active Vkappa gene promoters, and a 3' boundary sequence spanning 46 kilobases. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | plasmacytoma |
| PMID: | 15798207 |
| MONDO: | MONDO:0005615 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | 293T mouse CLDN18.2 |
| CVCL ID: | CVCL_UE61 |
| Cell Type: | plasmacytoma cell |
| Experiment Type: | Chromatin interaction assay, TF binding assay |
| High Throughput Method: | 3C-seq |
| Low Throughput Method: | ChIP-RT-qPCR |
About Target Gene
| Target gene : | Igk |
About TF
| TF name : | Tcf3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Tcf3 | CDO in myogenesis | reactome | 29 |
| Tcf3 | ID | netpath | 38 |
| Tcf3 | Notch-mediated HES/HEY network | pid | 48 |
| Tcf3 | Notch | netpath | 76 |
| Tcf3 | p38 signaling mediated by MAPKAP kinases | pid | 21 |
| Tcf3 | Regulation of nuclear SMAD2/3 signaling | pid | 82 |
| Tcf3 | Wnt | netpath | 118 |
| Tcf3 | Hs_Ectoderm_Differentiation_WP2858_89329 | wikipathways | 56 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer