Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04308
Species: Mus musculus
Position : chr6:70712244-70713044
Year: 2005
Title: Long-range interactions between three transcriptional enhancers, active Vkappa gene promoters, and a 3' boundary sequence spanning 46 kilobases.
Genome Build: mm39
Enhancer Type: Enhancer
Condition: Normal
PMID:  15798207
Tissue: blood
Tissue Ontology ID: UBERON:0000178
Cell Source: MPC-11
CVCL ID: CVCL_3857
Cell Type: plasma cell
Cell Ontology ID: CL:0000786
Experiment Type: Chromatin interaction assay; TF binding assay
Low Throughput Method: 3C; ChIP-qPCR; ChIP
About Target Gene
Target gene : Igk
About TF
TF name : Tcf3
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Tcf3 CDO in myogenesis reactome 29
Tcf3 ID netpath 38
Tcf3 Notch-mediated HES/HEY network pid 48
Tcf3 Notch netpath 76
Tcf3 p38 signaling mediated by MAPKAP kinases pid 21
Tcf3 Regulation of nuclear SMAD2/3 signaling pid 82
Tcf3 Wnt netpath 118
Tcf3 Hs_Ectoderm_Differentiation_WP2858_89329 wikipathways 56
Enhancer Associated Network
Overlapping Enhancers (mm39) 2 found
Enhancer ID Position Tissue Cell Disease
E_04307 chr6:70712244-70713044 blood plasma cell NA
E_04327 chr6:70712244-70713044 spleen B cell NA
Expression of Target Genes for the Enhancer