Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04314
Species: Mus musculus
Position : chr6:67556736-67558736
Year: 2005
Title: Long-range interactions between three transcriptional enhancers, active Vkappa gene promoters, and a 3' boundary sequence spanning 46 kilobases.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  15798207
Tissue: blood / hematopoietic system
Tissue Ontology ID: UBERON:0000178
Cell Source: B Cell,T Cell,MPC-11
Cell Type: T cell
Cell Ontology ID: CL:0000084
Experiment Type: TF-binding/chromatin assay; Chromatin interaction assay; Genetic-variant functional analysis
Low Throughput Method: ChIP-qPCR/ChIP; 3C
About Target Gene
Target gene : Igk
About TF
TF name : Tcf3
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Tcf3 CDO in myogenesis reactome 29
Tcf3 ID netpath 38
Tcf3 Notch-mediated HES/HEY network pid 48
Tcf3 Notch netpath 76
Tcf3 p38 signaling mediated by MAPKAP kinases pid 21
Tcf3 Regulation of nuclear SMAD2/3 signaling pid 82
Tcf3 Wnt netpath 118
Tcf3 Hs_Ectoderm_Differentiation_WP2858_89329 wikipathways 56
Enhancer Associated Network
Overlapping Enhancers (mm10) 2 found
Enhancer ID Position Tissue Cell Disease
E_04313 chr6:67556736-67558736 blood / hematopoietic system T cell NA
E_04315 chr6:67556736-67558736 blood / hematopoietic system T cell NA
Expression of Target Genes for the Enhancer