About Enhancer
| Enhancer ID: | E_04330 |
| Species: | Homo sapiens |
| Position : | chr11:5286080-5288080   |
| Year: | 2003 |
| Title: | A human globin enhancer causes both discrete and widespread alterations in chromatin structure. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 14585970 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | erythroid cell |
| Experiment Type: | Enhancer activity assay; chromatin regulatory assay |
| High Throughput Method: | Chromatin accessibility analysis |
| Low Throughput Method: | Reporter assay; DNase I hypersensitivity assay; ChIP; enhancer-core mutagenesis; RNase protection assay |
About Target Gene
| Target gene : | HBE1 |
About TF
| TF name : | NFE2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| NFE2 | Factors involved in megakaryocyte development and platelet production | reactome | 111 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02356 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02363 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02364 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02365 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_04273 | chr11:5286080-5288080 | blood / hematopoietic system | NA | NA |
Expression of Target Genes for the Enhancer