Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04340
Species: Homo sapiens
Position : chr14:92450000-92451800
Year: 2014
Title: EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: Ewing sarcoma
PMID:  25453903
MONDO: MONDO:0012817
Tissue: bone element
Tissue Ontology ID: UBERON:0001474
Cell Source: A-673
CVCL ID: CVCL_0080
Cell Type: Ewing sarcoma cell
Experiment Type: Functional perturbation assay
High Throughput Method: ChIP-seq; RNA-seq
Low Throughput Method: RT-RT-qPCR
About Target Gene
Target gene : VRK1
About TF
TF name : EWSR1::FLI1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer