About Enhancer
| Enhancer ID: | E_04360 |
| Species: | Mus musculus |
| Position : | chr6:60769316-60772093   |
| Year: | 2026 |
| Title: | Neuronal titration of Snca via enhancer disruption mitigates disease onset in a Parkinson's disease mouse model. |
| Genome Build: | mm39 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 41496593 |
| Tissue: | brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | Primary midbrain dopaminergic neurons |
| Cell Type: | dopaminergic neuron |
| Cell Ontology ID: | CL:0000700 |
| Experiment Type: | Functional perturbation assay; Endogenous enhancer perturbation; In vivo functional validation |
| Low Throughput Method: | CRISPR knockout, CRISPRi, RT-RT-qPCR, Western blot, FISH; Western blot; Mouse genetic deletion/knock-in |
About Target Gene
| Target gene : | Snca |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer