About Enhancer
| Enhancer ID: | E_04366 |
| Species: | Homo sapiens |
| Position : | chr11:5225400-5225774   |
| Year: | 2004 |
| Title: | An insulator blocks spreading of histone acetylation and interferes with RNA polymerase II transfer between an enhancer and gene. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 15371553 |
| Tissue: | bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| Low Throughput Method: | ChIP-RT-qPCR, RT-RT-qPCR, RNase protection assay, DNase I hypersensitivity assay, Restriction enzyme accessibility assay |
About Target Gene
| Target gene : | HBE1 |
About TF
| TF name : | NFE2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| NFE2 | Factors involved in megakaryocyte development and platelet production | reactome | 111 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02356 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02363 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02364 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02365 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_04539 | chr11:5224750-5226210 | urinary bladder | malignant cell | NA |
Expression of Target Genes for the Enhancer