Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04378
Species: Homo sapiens
Position : chr6:1619847-1620844
Year: 2016
Title: Disruptions in a cluster of computationally identified enhancers near FOXC1 and GMDS may influence brain development.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  26382291
Tissue: embryo
Tissue Ontology ID: UBERON:0000922
Cell Source: E11.5 transgenic mouse embryo
Experiment Type: Enhancer activity assay; Motif perturbation assay
High Throughput Method: Computational enhancer prediction; public epigenomic data integration
Low Throughput Method: Transient transgenic mouse Hsp68-lacZ reporter assay; X-gal staining; ZIC-motif deletion reporter assay
About Target Gene
Target gene : FOXC1
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 3 found
Enhancer ID Position Tissue Cell Disease
E_04394 chr6:1619348-1621343 brain NA NA
E_04395 chr6:1619348-1621343 brain NA NA
E_04379 chr6:1619847-1620844 embryo NA NA
Expression of Target Genes for the Enhancer