About Enhancer
| Enhancer ID: | E_04401 |
| Species: | Mus musculus |
| Position : | chr10:87376120-87376374   |
| Year: | 2021 |
| Title: | The Nestin neural enhancer is essential for normal levels of endogenous Nestin in neuroprogenitors but is not required for embryo development. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 34739481 |
| Tissue: | central nervous system |
| Tissue Ontology ID: | UBERON:0001017 |
| Cell Source: | Embryonic neuroprogenitor cells |
| Cell Type: | neural progenitor cell |
| Cell Ontology ID: | CL:0011020 |
| Experiment Type: | Functional perturbation assay, Enhancer activity assay; Enhancer activity assay; Endogenous enhancer perturbation; In vivo functional validation |
| Low Throughput Method: | CRISPR Knockout, qRT-PCR, In situ hybridization, Immunohistochemistry; CRISPR-Cas9 endogenous deletion/editing; Mouse genetic deletion/knock-in; In vivo phenotyping; Reporter assay |
About Target Gene
| Target gene : | Nes |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer