Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04407
Species: Mus musculus
Position : chr3:34756748-34761748
Year: 2023
Title: FACT regulates pluripotency through proximal and distal regulation of gene expression in murine embryonic stem cells.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  37542287
Tissue: embryo
Tissue Ontology ID: UBERON:0000922
Cell Source: murine embryonic stem cells (mESCs)
Cell Type: mouse embryonic stem cell
Cell Ontology ID: CL:0002322
Experiment Type: Enhancer activity assay, TF binding assay, Chromatin interaction assay
High Throughput Method: CUT&RUN
Low Throughput Method: Luciferase Reporter Assay; ChIP-RT-qPCR, qRT-PCR
About Target Gene
Target gene : Sox2
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 15 found
Enhancer ID Position Tissue Cell Disease
E_01316 chr3:34743178-34776096 NA NA NA
E_01317 chr3:34743178-34776096 NA NA NA
E_01318 chr3:34743178-34776096 NA NA NA
E_01385 chr3:34752523-34766449 embryo embryonic stem cell NA
E_01386 chr3:34752523-34766449 embryo embryonic stem cell NA
E_01387 chr3:34752523-34766449 embryo embryonic stem cell NA
E_01388 chr3:34752523-34766449 embryo embryonic stem cell NA
E_01439 chr3:34752523-34766449 embryo embryonic stem cell NA
E_01261 chr3:34755799-34762535 embryo embryonic stem cell NA
E_01262 chr3:34755799-34762535 embryo embryonic stem cell NA
E_01263 chr3:34755799-34762535 embryo embryonic stem cell NA
E_04995 chr3:34757100-34758037 embryoid body pluripotent stem cell NA
E_05017 chr3:34757100-34758037 NA embryonic stem cell NA
E_04996 chr3:34761100-34762000 embryoid body pluripotent stem cell NA
E_05018 chr3:34761100-34762000 NA embryonic stem cell NA
Expression of Target Genes for the Enhancer