About Enhancer
| Enhancer ID: | E_04421 |
| Species: | Homo sapiens |
| Position : | chr14:90847327-90849327   |
| Year: | 2012 |
| Title: | Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Congenital Limb Deformity |
| PMID: | 22265404 |
| Tissue: | blood / hematopoietic system |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | HCT 116 |
| CVCL ID: | CVCL_0291 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; Chromatin interaction assay; Disease-associated enhancer analysis |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; 3C; RT-qPCR/qPCR |
About Target Gene
| Target gene : | CALM1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
4 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04419 | chr14:90847327-90849327 | blood / hematopoietic system | malignant cell | Congenital Limb Deformity |
| E_04420 | chr14:90847327-90849327 | blood / hematopoietic system | malignant cell | Congenital Limb Deformity |
| E_04430 | chr14:90847327-90849327 | blood / hematopoietic system | malignant cell | Congenital Limb Deformity |
| E_04431 | chr14:90847327-90849327 | blood / hematopoietic system | NA | Congenital Limb Deformity |
Expression of Target Genes for the Enhancer