Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04432
Species: Homo sapiens
Position : chr14:61103201-61105984
Year: 2016
Title: Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  26884396
Tissue: kidney
Tissue Ontology ID: UBERON:0002113
Cell Source: 16-17 week human fetal nephron progenitors
Cell Type: metanephric mesenchyme stem cell
Cell Ontology ID: CL:0000324
Experiment Type: Enhancer activity assay; TF binding assay; Chromatin-state profiling
High Throughput Method: SIX1 ChIP-seq; SIX2 ChIP-seq; RNA-seq; ChIP-seq
Low Throughput Method: G0 transgenic lacZ::nGFP Reporter Assay; Immunofluorescence; ChIP
About Target Gene
Target gene : SIX1
About TF
TF name : SIX1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_04438 chr14:61101000-61104000 kidney nephron progenitor cell NA
E_04433 chr14:61103201-61105984 kidney metanephric mesenchyme stem cell NA
Expression of Target Genes for the Enhancer