About Enhancer
| Enhancer ID: | E_04438 |
| Species: | Homo sapiens |
| Position : | chr14:61101000-61104000   |
| Year: | 2016 |
| Title: | Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 26884396 |
| Tissue: | kidney |
| Tissue Ontology ID: | UBERON:0002113 |
| Cell Source: | 16-17 week human fetal nephron progenitor |
| Cell Type: | nephron progenitor cell |
| Experiment Type: | Enhancer activity assay, TF binding assay, Gene expression assay |
| High Throughput Method: | ChIP-seq; RNA-seq |
| Low Throughput Method: | LacZ transgenic reporter assay; ChIP-RT-qPCR; RT-RT-qPCR; Immunofluorescence |
About Target Gene
| Target gene : | SIX1 |
About TF
| TF name : | SIX2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
4 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04440 | chr14:61101000-61102000 | kidney | nephron progenitor cell | NA |
| E_04441 | chr14:61101000-61102000 | kidney | nephron progenitor cell | NA |
| E_04432 | chr14:61103201-61105984 | kidney | metanephric mesenchyme stem cell | NA |
| E_04433 | chr14:61103201-61105984 | kidney | metanephric mesenchyme stem cell | NA |
Expression of Target Genes for the Enhancer