About Enhancer
| Enhancer ID: | E_04452 |
| Species: | Homo sapiens |
| Position : | chr2:46578867-46579857   |
| Year: | 2022 |
| Title: | A pleiotropic hypoxia-sensitive EPAS1 enhancer is disrupted by adaptive alleles in Tibetans. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 36417539 |
| Tissue: | thoracic aorta |
| Tissue Ontology ID: | UBERON:0001515 |
| Cell Source: | TeloHAEC |
| CVCL ID: | CVCL_Z065 |
| Cell Type: | endothelial cell of thoracic aorta |
| Experiment Type: | Enhancer activity assay; Functional perturbation assay |
| High Throughput Method: | RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay; CRISPR/Cas9 deletion; RT-qPCR |
About Target Gene
| Target gene : | EPAS1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04502 | chr2:46578867-46579857 | kidney | HEK293T cell | NA |
Expression of Target Genes for the Enhancer